Myasthenia Gravis (MG)
MG is a chronic autoimmune disease, in which autoantibodies are produced against the body’s Acetylcholine receptors, resulting in their blockade, impairing impulse transmission and hence producing weakness of the skeletal muscles of the body. The hallmark of MG is muscle weakness that increases during periods of activity and improves after periods of rest. Facial, pharyngeal, abdominal, thoracic and limb muscles are commonly involved. Symptoms vary in type and severity, and dysphagia, dysarthria and weakness of the ocular muscles may constitute the presenting symptoms. The incidence of MG is 1 per 0.25m people, with a prevalence of 10 per 0.25m, and there are currently 35 registered patients under the GGHB.
Myasthenia Gravis Scotland
Myasthenia Gravis Association
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